Previously, we mentioned here the application SpotRM, which was launched in 2012. This was replaced in February 2016 with the much more advanced tool SpotRM+, which highlights potential hazards in your drawn structure by matching it with a rich set of structural alerts that have proven or likely associations with adverse clinical events.
The strength of this tool is its excellent backwards tracking to the facts and hypotheses that associate a certain reactive metabolite alert with examples of the drugs that contain the alert and cause, or cause not, adverse drug reactions.
It is also possible to perform text searches with key words.
SpotRM+ is a service provided by Awametox AB.