This site was set up with the intent to promote learning, especially among chemists, about reactive metabolites in the hope that fewer compounds with such issues will find their way into the design-make-test cycle. For this to happen a larger involvement of medicinal chemists is needed.
The homepage was initiated by Alf Claesson, former Principal Scientist in Medicinal Chemistry at AstraZeneca, Södertälje. Comments for additions & improvements are most welcome –
use the form below or make a direct phone call to +4670 553 7131.
Alf is also a consultant in the chemical toxicology field. He has led a workshop on reactive metabolites arranged by the Swedish Pharmaceutical Association in 2012 and given several in-house courses at pharmaceutical companies. Make contact via above phone number or homepage.